Our Facility
Purpose-built for the complete lifecycle of RNA nanotechnology and high-quality recombinant proteins — from synthesis and expression to purification, validation, and shipping.
Our Location
Strategic advantages of Dublin, Ohio
Dublin, Ohio
Nestled in Central Ohio's expanding life sciences hub, surrounded by a growing community of biotech innovators and research institutions.
Deep Scientific Talent
Proximity to The Ohio State University and Nationwide Children's Hospital — a national leader in gene and cell therapy research — gives us access to exceptional scientific expertise.
Nationally Connected
Located roughly 25 minutes from John Glenn Columbus International Airport, with Columbus's central position placing us within a one-day drive of nearly half the U.S. population.
Welcome to Dublin, Ohio, U.S.A.
Built for the full RNA and protein technology lifecycle
Our facility is purpose-built to support every stage of RNA and protein development — from custom RNA synthesis and nanostructure assembly to recombinant protein expression, purification, modification, and quality assessment.
By keeping design, production, purification, and quality control under a single roof, we support consistent workflows from molecular concept to research-ready RNA and protein products.
Capabilities
What we deliver from our facility
Integrated operations support RNA and protein products through production, purification, and application-appropriate quality control before they reach your bench.
Custom RNA Synthesis
In-house production of tailored RNA sequences with selected chemical modifications, fluorophores, targeting groups, and conjugation chemistries.
RNA Nanostructure Assembly
Programmable RNA nanostructure assembly and functionalization, with workflows developed around the intended architecture and application.
Recombinant Protein Production
Production of soluble and membrane proteins using bacterial, insect, and mammalian expression systems selected according to protein complexity, folding, and downstream use.
Protein Purification & Formulation
Chromatographic purification and application-specific formulation of soluble proteins, together with detergent-based purification and membrane-mimetic stabilization for membrane proteins.
QC & Validation
Every RNA construct and protein preparation undergoes rigorous quality control before shipping, helping ensure the reproducibility, consistency, and precision our customers can depend on.
Our Instruments & Equipment
Explore our specialized in-house instrument suites for high-throughput RNA synthesis, preparative chromatography, recombinant protein expression, and biophysical quality assurance.
RNA Instrumentation Suite
High-throughput solid-phase synthesis, preparative HPLC fractionation, microvolume UV-Vis quantification, VeriFlex thermal cycling, and sterile support infrastructure.
Protein Instrumentation Suite
FPLC size-exclusion chromatography (ÄKTA pure 25), 80,000 RPM preparative ultracentrifugation, dual-stack & CO₂ incubator shakers, and ultrasonic homogenization.
Comprehensive Facility Equipment
Instrument Directory
Rigorous validation and reproducible data from high-precision scientific hardware.
MerMade 48x Oligonucleotide Synthesizer
Automated parallel solid-phase synthesis of up to 48 modified RNA strands with >99% coupling efficiency.
Full Specifications →TGGE PowerPac Basic Gel Electrophoresis
Precise voltage and current control for native and denaturing PAGE evaluation of RNA integrity and sizing.
Full Specifications →Azure 2000 Gel Imaging System
5.4 MP, 16-bit high-resolution digital documentation under dual UV, blue light, and visible illumination.
Full Specifications →Gilson VERITY 281 Preparative HPLC
GX-281 liquid handler & 333/334 pumps for milligram-to-gram scale purification of synthetic oligonucleotides.
Full Specifications →NanoVue™ Plus Microvolume UV/Vis
0.5–5 µL droplet spectrophotometry with 200–900 nm wavelength scan and A260/A280/A230 ratio assessment.
Full Specifications →Savant DNA120 SpeedVac Concentrator
Centrifugal vacuum evaporation with oil-free diaphragm pump for rapid, bump-free RNA drying and solvent removal.
Full Specifications →Veriti™ 96-Well Thermal Cycler
Six independently controlled VeriFlex temperature zones for gradient optimization, annealing, and PCR workflows.
Full Specifications →SterileMax Series 1277 Steam Autoclave
34 L benchtop autoclave with dedicated 121°C liquid and 135°C labware sterilization cycles for RNase-free prep.
Full Specifications →ÄKTA pure 25 Protein Chromatography
Flexible FPLC size-exclusion chromatography (SEC) system for analytical and preparative protein purification.
Full Specifications →Optima LE-80K Ultracentrifuge
Up to 80,000 RPM high-speed preparative ultracentrifuge for protein complexes and macromolecular fractionation.
Full Specifications →Innova 44 Dual-Stack Incubator Shaker
High-capacity stacked incubator shaker supporting up to 5 L flasks (15.5 kg load) with programmable temperature control.
Full Specifications →VWR® 190 L Magnetic Drive CO₂ Shaker
190 L chamber with 0–20% CO₂ regulation and 4–60°C temperature range for recombinant suspension cultures.
Full Specifications →Pulse 150™ Ultrasonic Homogenizer
150 W ultrasonic cavitation with titanium horn for rapid cell disruption and downstream protein release.
Full Specifications →TGGE PowerPac Basic (Protein PAGE)
Reliable electrophoretic protein separation for purity verification and molecular weight confirmation.
Full Specifications →Azure 2000 Protein Gel Imager
Digital documentation of Coomassie Blue, silver stained, and fluorescently tagged protein gels.
Full Specifications →Instrumentation Inquiries
Partner with Our Analytical & Synthesis Facility
Need custom synthesis, SEC chromatography, or specialized biophysical testing? Discuss your project parameters with our laboratory directors.